Fatal brain abscess in a 36-year old poorly compliant renal transplantation recipient.

Abstract

In patients with organ transplantation, infections generally are considered to be the commonest cause of morbidity and mortality. The most common causes of infection after the first few weeks of transplantation are opportunistic infections as a result of immunosuppressive therapy which reduces the body’s immunity against microorganisms’ invasion. Thus, prophylaxis and regular surveillance for opportunistic infections are part of clinical guideline recommendations in the management of post renal transplant patients. Brain abscess is an uncommon but potentially life-threatening condition that requires prompt diagnosis and institution of effective treatment. The case presented highlights management problems in sub-Saharan Africa, where poor treatment compliance and late presentation, are common factors that contribute to poor treatment outcomes in patients with severe and life-threatening conditions.